DNA‐organic molecular amphiphiles: Synthesis, self‐assembly, and hierarchical aggregates

With the development of deoxyribonucleic acid (DNA) nanotechnology, various DNA nanostructures and devices have been constructed, which exhibit potential applications in material science biomedicine. Taking advantage programmability biocompatibility DNA, novel building block to chemically functionalize with hydrophobic organic molecules has attracted more attention. Driving by amphiphilicity, DNA-organic molecular amphiphiles demonstrated self-assemble or further induce hierarchically assemblies, providing novel-specific properties. In this minireview, we summarize recent progress including their synthesis, self-assembly behavior aqueous solution, amphiphilic based on hierarchical nano-structures. We briefly discuss perspective application amphiphiles.